Endocrine Abstracts

Introduction: The presence of heterophilic antibodies resulting in assay interference could lead to falsely high or low values in biochemical investigations. We present a case of a 5-year-old girl who had persistently high level of TSH despite Levothyroxine treatment.History: A five-year girl was found to have an elevated plasma TSH level (24.29 mU/L) with normal Free T4 (both measured using Abbott Alinity immunoassay) w...

Background: ROHHAD (rapid-onset obesity with hypoventilation, hypothalamic, autonomic dys-regulation) syndrome is an uncommon disease with fatal outcome. Rapidly progressive obesity in early childhood along with altered hypothalamic and autonomic function and hypoventilation are characteristic features. Neuroendocrine tumors complicate approximately 40% of the ROHHAD cases (ROHHAD-NET). Early diagnosis of this extreme rare disease is hampered by the absence of...